I've used two Wacom drawing tablets, and eventually got the Cintiq 13HD, and, overall, the transition was marvelous and I love it! If you're used to using and configuring a screenless Wacom tablet, the 13HD fits like a glove. 

I've had it for over a year now, and it's pretty great. Except, as you mentioned, the wiring is its biggest drawback. I think it's a device meant for a desk, because a set up where you're constantly moving it, like mine, is not good for it at all, and, from everything I've read up about it, there is no wireless accessory for it (because it requires a USB, Video, AND Power connection). I've had three consistent issues that revolve around its wiring:
1. The screen loses interactivity where the pen stops working on it (mouse and apps work just fine). Turning it off and turning it back on seems to fix it.
2. Weird RGB color distortion, where red or green artifacts appear on the screen. This seems to happen when I initially turn it on for a drawing session. Fiddling with the wire a bit seems to fix it.
3. The screen loses the picture entirely and seems to disconnect from my PC. Again, fiddling with the wire seems to fix it. This happens more often when something bumps into the contact point of the wire.

These issues don't happen very often, but enough to where I'm compelled to find solutions to it before I have an accident with it.

I find it to be a pretty good device that feels quite natural to draw on, but make sure it's stationary and not prone to a lot of movement.