Pros: Interesting characture design and nice exaggeration. Value range is strong and a strong amount of detail and texture. While veins usually don't form on the end of the nose it is disturbing and makes the drawing more striking.
Cons: The crows feet, why nicely exaggerated, is also over done and doesn't feel right because usually the converge at the very corner of the eye, but you are doing cartoon eyes so this makes it harder. The outside line work is fine and it has some nice variation of weight to it but bringing it inside to the eyes makes it feel inconstant. You could have also done without the outlining and used contrast to help define your image. Try reading this article I wrote on the various forms of contrast and how they can help you [link] .
Pros: Color, brush and texture techniques are strong. Good mood. Good human proportions.
Cons: I think the value ranger could be a little wider on the light side. A few more plains on her face for modeling would be called for, especially around the eyes, as except for you nose her face feels a bit flat. Also while your textures looks good I think you could push them a little further.
Not going to really touch composition though because of its nature of being a test painting.