Keyblade from Kingdom Hearts

Hey how about the chainsaw gun from Gears of War?

Chainsaw + Gun, I mean, come on.  

I have a major arsenal then...

portal gun (Portal)
nail gun (FEAR)
soul reaver (Legacy of kain)
masamune (final fantasy 7)
claws of hades (god of war 3)
ebony and ivory (devil may cry)
energy sword (halo)

Portal gun...
coolest thing ever.
or a pokeball. (Pokemon included)

Ouroborous-blazblue. :3 

I'd have to go for the Hidden Blade

Wooden Sword - Minecraft !

Laptop Gun from Perfect Dark 64.  Feeling lazy?  Just set it up and let it shoot for you.  aint life grand?

The Particle Cannon from the 2009 Wolfenstein game.
Nothing better then a lethal beam of Veil energy that completely vaporizes anyone unlucky enough to get caught in the line of fire. >)

Sephiroths masamune blade!

Either the Fire Arrows from Legend of Zelda or the Fire Rod from the same series.
Honestly, any weapon with fire will do.

Bayonetta's hair suit (but would this count as more of an ability?)

But someone might have to buy me a treadmill to go along with this. 

RYNO V from Ratchet and Clank, or the Needle Laser from Jak 3.

Either a portal gun and long fall boots, or that weapon in Halo that I really only know about because of RvB and not because I've played any of the Halo games (if anyone knows what I'm talking about: that knife-gun thing the Meta picks up)

Yeah yeah I know I should play the Halo games but money

Keyblade
Oh yeah....

Hilda's sword and lance - fruchtbare erde and glanzenda nova, then I would combine those with her fighting style - grosse erbshaft.

HK MP5 from counter strike!

ratatatatadat

Portal gun all the way

I'd have to go with the Unforgiven revolver from Borderlands but only the masher variant.

I would have to go with KOS-MOS' X-Buster. www.youtube.com/watch?v=E9Zt9R… 

Double barrel shot gun from Doom!

The beast infection weapon from Homeworld cataclysm with the beast under my control.