360. I prefer the interface and the exclusive games available on it. I also prefer the Xbox's controller over any other especially a mouse and keyboard. I know the graphics on a PS3 or PC game is usually going to be better, but better graphics does not make a game any better for me as long as I know what I'm looking at.
PC all the way baby. If I had to choose a console I'd probably choose the PS2 because that has some actually interesting and good designed games on it. Shadow of the Colossus, Killer 7, Prince of Persia: Sands of Time, Silent Hill 2. Yeah, those games I miss on my PC But the new consoles? blarg...
I prefer PS2 so I can play DVDs as well as PS and PS2 games. I also have a Wii. I used to have a WiiSlim, but downgraded it when I found out it couldn't play Gamecube games.
So, all in all, I have my PS2, my Wii, a 3DS, and my laptop
XBox 360. I like the firmness of the controller and the variety of buttons on it. I really like XBox Live and I find it more amusing to play games on that console. I do like the PS2, but mine's not working very well anymore.